Robust coordination and organization in large ensembles of nonlinear oscillatory units play a vital role in a wide range of natural and engineered system.The control of self-organizing network-coupled systems has recently seen significant attention, but largely in the context of modifying or augmenting existing structures.This leaves a gap in our u
Extracellular vesicles (EVs) are involved in a wide range of physiological and pathological processes by shuttling material out of and between cells.Tissue EVs look trail fusion pedals may thus lend insights into disease mechanisms and also betray disease when released into easily accessed biological fluids.Since brain-derived EVs (bdEVs) and their
Clear cell renal cell carcinoma (ccRCC) is the most common and lethal form of urological cancer diagnosed globally.Mutations of the von Hippel-Lindau (VHL) tumor-suppressor gene and the resultant overexpression of hypoxia-inducible factor (HIF)-1α protein are considered hallmarks of ccRCC.Persistently activated HIF-1α is associated with i
Serum albumin is a globular protein which is most abundant in human that binds remarkably with wide range of drugs.A reliable prediction of protein and drug binding at the atomic level by optical spectroscopy and molecular modeling methods provides the basis for the design of new drug compounds.In the current study, A newly synthesized 3-(1-Phenyls